Seminars in Oncology Nursing
Volume 20, Issue 1 , Pages 22-29 , February 2004

Assessment and measurement of oral mucositis

  • June Eilers

      Affiliations

    • Department of Oncology/Hematology, The Nebraska Medical Center, Omaha, NE, USA
    • Corresponding Author InformationAddress reprint requests to June Eilers, PhD, APRN, BC, 6604 S 86th St, Ralston, NE 68127, USA
    • ,
  • Joel B. Epstein

      Affiliations

    • Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, University of Illinois, Chicago, IL, USA

References 

  1. Clarkson JE, Worthington HV, Eden OB. Interventions for preventing oral mucositis for patients with cancer receiving treatment. Cochrane Database Syst Rev. 2003;3:CD000978
  2. Rubenstein EB, et al. Clinical practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis. Cancer 2003 (in press).
  3. Plevova P. Prevention and treatment of chemotherapy- and radiotherapy-induced oral mucositis (a review). Oral Oncology. 1999;35:453–454
  4. Avritscher EBC, Cooksley C, Elting LS. Scope and epidemiology of oral and gastrointestinal mucositis. Semin Oncol Nurs. 2004;20: xx-xx
  5. Streiner DL, Norman GR. Health Measurement Scales (A Practical Guide to Their Development and Use). New York, NY: Oxford; 1995;
  6. Sitzia J, Dikken C, Hughes J. Psychometric evaluation of a questionnaire to document side-effects of chemotherapy. J Adv Nurs. 1997;25:999–1007
  7. Jacobson SF. Evaluating instruments for use in clinical nursing research. In:  Frank-Stromborg M,  Olsen SJ editor. Instruments for Clinical Health-Care Research. Boston, MA: Jones & Bartlett; 1997;p. 3–19
  8. Guyatt GH, Kisrshner B, Jaeschke R. Measuring health status (what are the necessary measurement properties?). J Clin Epidemiol. 1992;45:1341–1345
  9. McGuire DB, Peterson DE. Introduction. Semin Oncol Nurs. 2004;20: xx-xx
  10. Consensus development conference on oral complications of cancer therapies (diagnosis, prevention, and treatment). Bethesda, MD: National Institutes of Health; 1990; No. 9
  11. National Cancer Institute . Mucosal injury in cancer patients (new strategies for research and treatment). J Natl Cancer Inst Monogr. 2001;29:1–51
  12. Bellm LA, Epstein JB, Rose-Ped A, et al.  Patient reports of complications of bone marrow transplantation. Support Care Cancer. 2000;8:33–39
  13. Rose-Ped AM, Bellm LA, Epstein JB, et al.  Complications of radiation therapy for head and neck cancers. The patient’s perspective. Cancer Nurs. 2002;25:461–467 quiz 468–469
  14. Sonis ST. Mucositis as a biological process (a new hypothesis for the development of chemotherapy-induced stomatotoxicity). Oral Oncol. 1998;34:39–43
  15. Sonis ST. Pathobiology of mucositis. Semin Oncol Nurs. 2004;20: xx-xx
  16. Epstein J, Schubert M. Oral mucositis in myelosuppresive cancer therapy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;88:273–276
  17. Doherty KM. Closing the gap in prophylactic antiemetic therapy (patient factors in calculating the emetogenic potential of chemotherapy). Clin J Oncol Nurs. 1999;3:113–119
  18. Eilers J. When the mouth tells us more than it says-the impact of mucositis on quality of life. Oncol Support Care Q. 2003;1:31–43
  19. Bonadonna G, Valagussa P. Dose-response effect of adjuvant chemotherapy in breast cancer. N Engl J Med. 1981;304:10–15
  20. Frei E, Canellos GP. Dose (a critical factor in cancer chemotherapy). Am J Med. 1980;69:585–594
  21. Hryniuk W, Bush H. The importance of dose intensity in chemotherapy of metastatic breast cancer. J Clin Oncol. 1984;2:1281–1288
  22. Epstein JB, Tsang AGF, Warkentin D, et al.  The role of salivary function in modulating chemotherapy-induced oropharyngeal mucositis (a review of the literature). Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002;94:39–44
  23. Janken JK, Beal LF, Fieler VK. Measuring mouth moisture (a case study in instrument development). Clin Nurse Spec. 1989;3:114–118
  24. Epstein JB, Schubert MM. Managing pain in mucositis. Semin Oncol Nurs. 2004;20:30–37
  25. DeWalt EM, Haines AK. The effects of specified stressors on healthy oral mucosa. Nurs Res. 1969;18:22–27
  26. Ezzone S, Jolly D, Replogle K, et al.  Survey of oral hygiene regimens among bone marrow transplant centers. Oncol Nurs Forum. 1993;20:1375–1381
  27. Graham KM, Pecoraro DA, Ventura M, et al.  Reducing the incidence of stomatitis using a quality assessment and improvement approach. Cancer Nurs. 1993;16:117–122
  28. Yeager KA, Webster J, Crain M. Implementation of an oral care standard for leukemia and transplantation patients. Cancer Nurs. 2000;23:40–47 quiz 47–48
  29. Eilers J. Stomatitis as a side effect of cancer treatment. Quality of Life - A Nursing Challenge. 2003;5:68–74
  30. Epstein JB, Phillips N, Parry J, et al.  Quality of life, taste, olfactory and oral function following high-dose chemotherapy and allogeneic hematopoietic cell transplantation. Bone Marrow Transplant. 2002;30:785–792
  31. Dodd MJ, Dibble S, Miaskowski C, et al.  A comparison of the affective state and quality of life of chemotherapy patients who do and do not develop chemotherapy-induced oral mucositis. J Pain Symptom Manage. 2001;21:498–505
  32. Estabrooks CA, Hodgins MJ. Clinical significance (Play it again Sam…). Clin Nurs Res. 1996;5:371–375
  33. Stokman MA, Spijkervet FK, Wymanga AN, et al.  Quantification of oral mucositis due to radiotherapy by determining viability and maturation of epithelial cells. J Oral Pathol Med. 2002;31:153–157
  34. Oral assessment. In:  Griffiths J,  Boyle S editor. A Colour Guide to Holistic Oral Care (A Practical Approach). Aylesbury, England: Mosby-Year Book; 1993;p. 87–98
  35. Hyland SA. Assessing the oral cavity. In:  Frank-Stromborg M,  Olsen SJ editor. Instruments for Clinical Health-Care Research. Boston, MA: Jones & Barlett; 1997;p. 519–527
  36. Beck S. Impact of a systematic oral care protocol on stomatitis after chemotherapy. Cancer Nurs. 1979;2:185–199
  37. Eilers J, Berger AM, Petersen MC. Development, testing, and application of the oral assessment guide. Oncol Nurs Forum. 1988;15:325–330
  38. Kolbinson DA, Schubert MM, Flournoy N. Early oral changes following bone marrow transplantation. Oral Surgery. 1988;66:130–138
  39. Schubert MM, Williams BE, Lloid ME, et al.  Clinical assessment scale for the rating of oral mucosal changes associated with bone marrow transplantation. Development of an oral mucositis index. Cancer. 1992;69:2469–2477
  40. McGuire DB, Peterson DE, Muller S, et al.  The 20 item oral mucositis index (reliability and validity in bone marrow and stem cell transplant patients). Cancer Invest. 2002;20:893–903
  41. Western Consortium for Nursing Research . Priorities for cancer nursing research (a Canadian replication). Cancer Nurs. 1987;10:319–326
  42. WHO Handbook for Reporting Results for Cancer Treatment. Geneva, Switzerland: World Health Organization; 1979; Available at http://whqlibdoc.who.int/publications/9241700483.pdf (accessed September 18, 2003)
  43. Common Toxicity Criteria v3.0. Bethesda, MD: National Cancer Institute; 2003; Available at http://ctep.cancer.gov/forms/CTCAEv3.pdf. (accessed September 18, 2003)
  44. Cox JD, Stetz J, Pajak TF. Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC). Int J Radiat Oncol Biol Phys. 1995;31:1341–1346
  45. Sonis ST, Eilers JP, Epstein JB, et al.  Validation of a new scoring system for the assessment of clinical trial research of oral mucositis induced by radiation or chemotherapy. Mucositis Study Group. Cancer. 1999;85:2103–2113
  46. Spijkervet FK, vanSaene HK, Panders AK, et al.  Scoring irradiation mucositis in head and neck cancer patients. J Oral Pathol Med. 1989;18:167–171
  47. Fox PC, Busch KA, Baum BJ. Subjective reports of xerostomia and objective measures of salivary gland performance. J Am Dent Assoc. 1987;115:581–584

PII: S0749-2081(03)00136-0

doi: 10.1053/j.soncn.2003.10.005

Seminars in Oncology Nursing
Volume 20, Issue 1 , Pages 22-29 , February 2004

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