Seminars in Oncology Nursing
Volume 22, Issue 1 , Pages 36-42, February 2006

The Effects of Neuromuscular Alterations in Elders With Cancer

  • Constance Visovsky

      Affiliations

    • Corresponding Author InformationAddress correspondence to Constance Visovsky, PhD, RN, ACNP, University of Nebraska Medical Center, College of Nursing, 985330 Nebraska Medical Center, Omaha, NE 68198-5330

University of Nebraska Medical Center, College of Nursing, Omaha, NE.

Objectives

To review the effects of normal aging on declines in function of peripheral nerves and muscles and the additive effects of chemotherapy and comorbidity in elders undergoing cancer treatment.

Data Sources

Research studies and published articles.

Conclusion

Chemotherapy negatively affects physical functioning and recovery in elders with cancer through neurotoxicity and myotoxicity. Intact sensory nerves and muscles are crucial in maintaining physical function and independence for elders.

Implications for Nursing Practice

While older patients with cancer may benefit from chemotherapy, clinical practices to minimize toxicities, provide monitoring for functional decline, and intervene to maintain function are needed.

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PII: S0749-2081(05)00121-X

doi:10.1016/j.soncn.2005.10.010

Seminars in Oncology Nursing
Volume 22, Issue 1 , Pages 36-42, February 2006