Seminars in Oncology Nursing
Volume 22, Issue 3 , Pages 185-193 , August 2006

Management of Malignant Fungating Wounds in Advanced Cancer

  • Susie Seaman

      Affiliations

    • Corresponding Author InformationAddress correspondence to Susie Seaman, MSN, FNP, CWOCN, Grossmont Hospital Wound Healing Center, 5555 Grossmont Center Drive, La Mesa, CA 91942

References 

  1. Young CV . The effects of malodorous fungating malignant wounds on body image and quality of life . J Wound Care . 2005;14:359–362
  2. Lookingbill DP , Spangler N , Sexton FM . Skin involvement as the presenting sign of internal carcinoma . J Am Acad Dermatol . 1990;22:19–26
  3. Lookingbill DP , Spangler N , Helm KF . Cutaneous metastases in patients with metastatic carcinoma (A retrospective study of 4020 patients) . J Am Acad Dermatol . 1993;29:228–236
  4. Ambrogi V , Nofroni I , Tonini G , et al.  Skin metastasis in lung cancer (Analysis of a 10-year experience) . Oncol Rep . 2001;8:57–61
  5. Saeed S , Keehn CA , Morgan MB . Cutaneous metastasis (A clinical, pathological, and immunohistochemical appraisal) . J Cutan Pathol . 2004;31:419–430
  6. Cormio G , Capotorto M , Di Vagno G , et al.  Skin metastases in ovarian carcinoma (A report of nine cases and a review of the literature) . Gynecol Oncol . 2003;90:682–685
  7. Pitman KT , Johnson JT . Skin metastases from head and neck squamous cell carcinoma (Incidence and impact) . Head Neck . 1999;21:560–565
  8. Mueller TJ , Wu H , Greenberg RE , et al.  Cutaneous metastases from genitourinary malignancies . Urology . 2004;63:1021–1026
  9. Carroll MC , Fleming M , Chitambar CR , et al.  Diagnosis workup, and prognosis of cutaneous metastases of unknown primary origin . Dermatol Surg . 2002;28:533–535
  10. Schwartz RA . Cutaneous metastatic disease . J Am Acad Dermatol . 1995;33:161–182
  11. Ivetic O , Lyne PA . Fungating and ulcerating malignant lesions (A review of the literature) . J Adv Nurs . 1990;15:83–88
  12. Cohen PR . Skin clues to primary and metastatic malignancy . Am Fam Physician . 1995;51:1199–1204
  13. Wilson V . Assessment and management of fungating wounds (A review) . Br J Community Nurs . 2005;10:S28–S34
  14. Collier M . The assessment of patients with malignant fungating wounds - A holistic approach (Part 1) . Nurs Times . 1997;93(suppl):1–4
  15. Grocott P , Cowley S . The palliative management of fungating malignant wounds – Generalising from multiple case study data using a system of reasoning . Int J Nurs Stud . 2001;38:533–545
  16. Naylor W . Assessment and management of pain in fungating wounds . Br J Nurs . 2001;10(suppl 22):S33–S36
  17. Bowler PG , Davies BJ , Jones SA . Microbial involvement in chronic wound malodour . J Wound Care . 1999;8:216–218
  18. Clark J . Metronidazole gel in managing malodorous fungating wounds . Br J Nurs . 2002;11(suppl 6):S54–S60
  19. Bradley M . When healing is not an option (Palliative care as the primary treatment goal) . Adv Nurse Pract . 2004;12:50–55
  20. Bates-Jensen BM , Early L , Seaman S . Skin disorders. In:  Ferrell BR ,  Coyle N editor. Textbook of Palliative Nursing . Oxford: Oxford University Press; 2001;p. 204–244
  21. Haisfield-Wolfe ME , Baxendale-Cox LM . Staging of malignant cutaneous wounds (A pilot study) . Oncol Nurs Forum . 1999;26:1055–1064
  22. van Leeuwen BL , Houwerzijl M , Hoekstra HJ . Educational tips in the treatment of malignant ulcerating tumours of the skin . Eur J Surg Oncol . 2000;26:506–508
  23. Grocott P . The management of fungating wounds . J Wound Care . 1999;8:232–234
  24. Seaman S . Dressing selection in chronic wound management . J Am Podiatr Med Assoc . 2002;92:24–33
  25. Gomolin IH , Brandt JL . Topical metronidazole therapy for pressure sores of geriatric patients . J Am Geriatr Soc . 1983;31:710–712
  26. Rice TT . Metronidazole use in malodorous skin lesions . Rehabil Nurs . 1992;17:244–245 255
  27. Whedon MA . Practice corner (What methods do you use to manage tumor-associated wounds?) . Oncol Nurs Forum . 1995;22:987–990
  28. Poteete V . Case study (Eliminating odors from wounds) . Decubitus . 1993;6:43–46
  29. Finlay IG , Bowszyc J , Ramlau C , et al.  The effect of topical 0.75% metronidazole gel on malodorous cutaneous ulcers . J Pain Symptom Manage . 1996;11:158–162
  30. Holloway GA , Johansen KH , Barnes RW , et al.  Multicenter trial of cadexomer iodine to treat venous stasis ulcer . West J Med . 1989;151:35–38
  31. Danielsen L , Cherry GW , Harding K , et al.  Cadexomer iodine in ulcers colonised by pseudomonas aeruginosa . J Wound Care . 1997;6:169–172
  32. Cormier AC , McCann E , McKeithan L . Reducing odor caused by metastatic breast cancer skin lesions . Oncol Nurs Forum . 1995;22:988–999
  33. Gagnon B , Mancini I , Pereira J , et al.  Palliative management of bleeding events in advanced cancer patients . J Palliat Care . 1998;14:50–54
  34. Pereira J , Phan T . Management of bleeding in patients with advanced cancer . The Oncologist . 2004;9:561–570
  35. Grocott P . Controlling bleeding in fragile fungating tumors . J Wound Care . 1998;7:342
  36. Rankin EM , Rubens RD , Reidy JF . Transcatheter embolisation to control severe bleeding in fungating breast cancer . Eur J Surg Oncol . 1988;14:27–32
  37. Broadley KE , Kurowska A , Dick R , et al.  The role of embolization in palliative care . Palliat Med . 1995;9:331–335
  38. Coldwell DM , Sewell PE . The expanding role of interventional radiology in the supportive care of the oncology patient (from diagnosis to therapy) . Semin Oncol . 2005;32:169–173
  39. Chaloupka JC , Mangla S , Huddle DC , et al.  Evolving experience with direct puncture therapeutic embolization for adjunctive and palliative management of head and neck hypervascular neoplasms . Laryngoscope . 1999;109:1864–1872
  40. Murakami M , Kuroda Y , Sano A , et al.  Validity of local treatment including intraarterial infusion chemotherapy and radiotherapy for fungating adenocarcinoma of the breast . Am J Clin Oncol . 2001;24:388–391
  41. Sawynok J . Topical and peripherally acting analgesics . Pharmacol Rev . 2003;55:1–20
  42. Back IN , Finlay I . Analgesic effect of topical opioids on painful skin ulcers . J Pain Symptom Manage . 1995;10:493
  43. Krajnik M , Zbigniew Z . Topical morphine for cutaneous cancer pain . Palliative Med . 1997;11:325
  44. Zeppetella G , Paul J , Ribeiro MD . Analgesic efficacy of morphine applied topically to painful ulcers . J Pain Symptom Manage . 2003;25:555–558
  45. Zeppetella G , Ribeiro MD . Morphine in intrasite gel applied topically to painful ulcers . J Pain Symptom Manage . 2005;29:118–119
  46. Ballas SK . Treatment of painful sickle cell leg ulcers with topical opioids . Blood . 2002;99;:1096
  47. van Sonnenberg E , Shankar S , Parker L , et al.  Palliative radiofrequency ablation of a fungating symptomatic breast lesion . AJR Am J Roentgenol . 2005;184:S126–S128
  48. Fritz P , Hensley FW , Berns C , et al.  Long-term results of pulsed irradiation of skin metastases from breast cancer . Strahlenther Onkol . 2000;176:368–376
  49. Seegenschmiedt MH , Keilholz L , Altendorf-Hofmann A , et al.  Palliative radiotherapy for recurrent and metastatic malignant melanoma: prognostic factors for tumor response and long-term outcome: A 20-year experience . Int J Radiat Oncol Biol Phys . 1999;44:607–618
  50. Leonard R , Hardy J , van Tienhoven G , et al.  Randomized double-blind, placebo-controlled, multicenter trial of 6% miltefosine solution, a topical chemotherapy in cutaneous metastases from breast cancer . J Clin Oncol . 2001;19:4150–4159
  51. Piggin C . Malodorous fungating wounds (uncertain concepts underlying the management of social isolation) . Int J Palliat Nurs . 2003;9:216–221
  52. Lund-Nielsen B , Müller K , Adamsen L . Malignant wounds in women with breast cancer (Feminine and sexual perspectives) . J Clin Nurs . 2004;14:56–64

PII: S0749-2081(06)00060-X

doi: 10.1016/j.soncn.2006.04.006

Seminars in Oncology Nursing
Volume 22, Issue 3 , Pages 185-193 , August 2006

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