Advances in Hormonal Therapy for Breast Cancer
Objectives
To describe recent developments in hormonal therapy for breast cancer, focusing on SERMs and AIs.
Data Sources
Published journal articles and texts, research reports and monographs, government publications, and professional organization guidelines.
Conclusion
Research continues to identify the effectiveness of hormonal therapy in breast cancer, including adjuvant treatment in early and advanced stages as well as a chemopreventive measure. The individual drug profile must be evaluated for safety and efficacy, and the impact on QOL must be considered.
Implications for Nursing Practice
It is imperative that oncology nurses understand the physiology, application, risks, and benefits of hormonal therapies.
Key Words: Hormonal therapy, SERM, Aromatase inhibitor, Menopausal symptoms
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PII: S0749-2081(06)00161-6
doi:10.1016/j.soncn.2006.11.008
© 2007 Elsevier Inc. All rights reserved.
