Managing Treatment Side Effects in Advanced Breast Cancer
Objectives
To compare and contrast the side-effect profiles of antineoplastic therapy options used in the treatment of metastatic breast cancer.
Data Sources
Published research articles, abstracts, and clinical experience.
Conclusion
Novel and existing antineoplastic agents used in the treatment of metastatic breast cancer generally have mild side effects, but can have the potential for serious reactions. Nausea/vomiting, diarrhea, stomatitis/mucositis, and dermatologic and cardiovascular effects are common. Strategies such as dietary changes, over-the-counter remedies, and dose modification can be used to counteract these mild effects.
Implications for Nursing Practice
The oncology nurse should be aware of common adverse events associated with antineoplastic agents, recognize early side-effect signs, and be ready with effective strategies to mitigate side effects when and if they occur.
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The development of this article was based on a presentation given by S. Moore at the 2006 Oncology Nursing Society's 7th Annual Institutes of Learning; the author received an honorarium through an educational grant from GlaxoSmithKline.
Ms Moore has served as a member of the Speaker's Bureau for Roche Laboratories, Genentech Inc., and GlaxoSmithKline.
PII: S0749-2081(07)00092-7
doi:10.1016/j.soncn.2007.10.005
© 2007 Elsevier Inc. All rights reserved.
