Seminars in Oncology Nursing
Volume 25, Issue 2, Supplement 1 , Pages S1-S7, May 2009

Understanding the Genetic Determinants of Pain and Pain Management

  • Christine Miaskowski

      Affiliations

    • Corresponding Author InformationAddress correspondence to Christine Miaskowski, RN, PhD, FAAN, University of California, San Francisco, 2 Koret Way – N631Y, San Francisco, CA 94143-0610

Objectives

To review the role of inter-individual differences in responses to pain and analgesics and to describe how these differences impact the effectiveness of therapies for patients who have cancer pain.

Data Sources

Published research articles and clinical experience.

Conclusion

Individuals' genetic predisposition can affect their therapeutic response to analgesics. With the rapidly advancing field of pharmacogenetics, soon our therapeutic strategies will be targeted based on patients' genetics.

Implications for Nursing Practice

Oncology nurses will be better able to individualize their therapeutic strategies for patients in pain.

Key Words: Cancer pain, genetics, pharmacogenomics

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 Based on a symposium held at the 2008 Oncology Nursing Society Congress.

PII: S0749-2081(09)00030-8

doi:10.1016/j.soncn.2009.03.012

Seminars in Oncology Nursing
Volume 25, Issue 2, Supplement 1 , Pages S1-S7, May 2009

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